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While there is a mild induction of the inflammatory response for the 100- and 200-nm topographies, these growth conditions also supported expressions of genes that would be responsible in the prevention of foam cell formation and the removal of foam cells, suggesting potential benefits.
Similar to in vitro data, infection with B.anthracis in vivo results in only mild induction of IFN signaling as determined by STAT1 phosphorylation.
Indeed, the HSP90-RNAi set may more faithfully reveal effects of reduced HSP90, as these lines, unlike individual constitutive HSP90-TDNA lines, display neither compensation through upregulation of the inducible isoform nor mild induction of the heat-shock response.
In an early study, we observed a mild induction of basal but not Tat-induced HIV-1 transcription by PP2A-inhibitory low concentrations of okadaic acid [ 50].
Consistent with mild induction of apoptosis by single knockdown of PLC δ3, the amount of phosphorylated PKC θ was slightly decreased in PLC δ3 single-knockdown H9c2 cells.
TGF-β1 markedly decreased expression of gamma-glutamylcysteine synthetase [ 277, 292], whereas the acute inflammatory cytokine TNF-alpha caused a mild induction of this enzyme [ 277].
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In conclusion, available data do not support the use of pediatric regimens in adult LCH, indicating that the concept of mild induction followed by maintenance therapy probably cannot be translated to adults.
Scientists such as LaBerge devised techniques to induce lucid dreams, most notably the Mild technique (mnemonic induction of lucid dreams).
These findings corroborated that the vaccine formulation is highly safe in mice model and is relatively mild in the induction of inflammatory cytokines and cellular changes in human cell lines.
Figure 1 clearly demonstrated a mild, but noticeable induction of hGBP1 and 2 transcripts 24 h after treatment with 0.05 ng/ml dose of IFNγ, a dose that is inefficient in inhibiting the growth of various chlamydial strains and species as evaluated by microscopy and inclusion forming unit (IFU) assay.
Only a mild tumor-selective induction of TNFRSF10B (DR5/TRAILR2) was observed.
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