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The number of prisoners held in the Bastille at any one time declined sharply towards the end of Louis's reign; the prison contained ten prisoners in September 1782 and, despite a mild increase at the beginning of 1788, by July 1789 only seven prisoners remained in custody.
All groups were further divided into 3 groups to represent the developing course in 0, 1, and 4 weeks after onset of type 2 DM. Figure 1(b) shows that Ccr in the DM group had a mild increase at week 1 but a significant increase at week 4, demonstrating that this model had developed the hyperfiltration stage and mimicked clinical glomerular hyperfiltration of DN well.
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Impedance spectrograms showed a mild increase in impedance at high frequencies but a more pronounced decrease in impedance at mid to low frequencies.
The mild increase in the hemoglobin level at 4 weeks (peak of 13.8 g/dl) was not associated with thromboembolic events and the use of EPO was not associated with hypertension in the treated animals.
However, for both TDP-43CTF and TDP-43FFLL,ΔNLS we observed a transient mild increase in Casp-3+ motor neurons at 2 days after transfection (Fig. 5C); which, however, was apparently insufficient to result in measurable reduction of motor neuron numbers at later stages (Fig. 5B).
Moreover, increasing dsRNA concentrations led to a rather mild increase of phenotypic severity but even at highest concentrations the "empty egg" phenotype was not increased beyond background.
Due to the presence of hypokalemia, other causes of hypertension were researched leading to the discovery of hyperreninemia (236 μUI/ml) with mild hyperaldosteronism, and a mild increase of the renal artery resistance at ultrasound.
Preliminary results obtained from four independent experiments seem to indicate that exposure of maturing DCs to spermine slightly promotes their maturation, as assessed by a dose-dependent mild increase of DC expression of CD83 – at levels similar to those observed in vivo – and of CD40.
Loss of uig-1 function led at best to a mild increase, if any, of persistent cell corpses on its own.
In our opinion a mild increase of TnI individuates a group of patients at low risk of cardiac adverse events.
At E16, we observed a mild increase in cell proliferation in the KO, as measured by BrdU incorporation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com