Sentence examples for mild hepatic dysfunction from inspiring English sources

The Japanese literature reports 20 cases of diabetes mellitus-associated hepatomegaly and mild hepatic dysfunction attributed (especially in cases of type 1 diabetes) to chronic overinsulinization [ 16].

Mild hepatic dysfunction (grade II) was seen in 1 case, however it was only temporary and disappeared in spite of the continuance of DC injections.

The experience with bendamustine has demonstrated insignificant variation in its pharmacokinetics based on age, gender, and existence of mild to moderate renal dysfunction or mild hepatic dysfunction.

There was an increase in the transaminase levels and the bilirubin and there was evidence of mild hepatic dysfunction as evidenced by an increase of INR; however, the liver abnormalities self-resolved in a few weeks.

Patients with mild hepatic dysfunction (SOFA score = 1) had one-half the odds of developing liver impairment compared with those with no dysfunction (OR = 0.49; 95% CI = 0.30 to 0.79; P = 0.0032).

Specifically, 77 % of cases with hepatic encephalopathy and/or a Maddrey DF ≥32 had AH as a primary diagnosis compared with only 59%% of those with mild hepatic dysfunction.

Peak plasma concentrations of oxycodone and noroxycodone are higher in patients with mild-to-moderate hepatic dysfunction or mild-to-severe renal dysfunction, and oxymorphone concentrations are lower in patients with impaired hepatic function [ 36– 36].

Long-term toxicity including mild to moderate hepatic dysfunction(17/55), abdominal pain and diarrhea(15/55), transient albuminuria(2/55) and Mild elevation of blood urea nitrogen and creatinine(1/55) was observed in this cohort.

Mild hepatic and renal dysfunction was suspected.

Indeed, Twelves et al (1999) demonstrated that mild to moderate hepatic dysfunction has no clinically significant influence on the pharmacokinetic parameters of capecitabine and its metabolites.

According to the prescribing information summary, dose adjustments are required for patients with mild to moderate hepatic dysfunction (Child-Pugh class A and B).