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IFN-γR immunostaining in LG at 4 and 8 W showed very minimal immunoreactivity in glandular tissue in IL-17/IFNγ DKO while a mild expression was seen in CD25/IL-17/IFN-γ CD25/IL-17/IFN-γ CD25/IL-17/IFN-γ
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Mild resistin expression was observed in the cytoplasm of some muscle fibres.
In a recent study [ 28], miR-146a was reported to be expressed mostly in OA cartilage showing mild scores and its expression was stimulated in normal chondrocytes by IL-1β.
In the mouse model of mild (20 weeks of HFD) and severe hepatosteatosis (40 weeks of HFD), p53 expression increased in both mild and severe hepatic steatosis, and increased DRAM expression and autophagy were identified in mild hepatosteatosis, whereas higher BAX expression was observed in severe hepatosteatosis [ 33].
In general the symptom expression was very mild and at most phenotype of stage 2 occurred.
IL-17F expression was increased in mild to moderate and severe asthma, but not in COPD.
The protein expression was classified as mild, moderate and intense on the basis of the intensity of immunostaining.
The quantification of lung YKL-40 expression revealed that YKL-40 expression was higher in mild asthma patients than healthy controls.
This expression was usually of mild to moderate intensity, and when stratified using the cutoff used for the tumors, all were considered negative for SIAH2.
In Group S + B, the changes of Bcl-2, Bax and Caspase-3 expression was a relatively mild compared with Group S (P < 0.05).
The quantification of lung YKL-40 expression revealed that YKL-40 expression was higher in mild asthma patients than in healthy controls (19.15% [14.60-20.75%] vs. 11.70% [9.01-13.85%]; p = 0.006).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com