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In our model, upon mild dosing of HU, DNA damage caused cell cycle arrest and overwhelmed DNA damage repair pathways whose downregulation further magnified the DNA damage effects.
Therefore, for further experimentations, we opted to use mild dosing of HU (8 mM HU, 12 h) that produced persistent DSBs.
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CATALDI MADONNA, TONÌ 1998: $35 Raspberry and chocolate flavors, with a mild dose of oak.
It didn't help that Asamoah Gyan was out with what's been described as "a mild dose" of malaria.
Shinji Kagawa was found to be suffering from a mild dose of the flu upon his return from international duty with Japan.
The bricks, by contrast, only suffered a mild dose of paint and the acid aspersions of the Sunday Times in 1976.
For MEPs who detest the EU and all its works, Griffin and Brons also sounded as though they were catching a mild dose of Euro-fever.
It's probably a mild dose of E Coli or Cryptosporidium enteritis but in those sewage-infested waters he could also catch dysentery, meningitis, or legionnaires' disease.
Mr. Bush's intermittently dismissive tone toward Senator John McCain in an interview on Wednesday suggested he has at least a mild dose of that nomination hubris.
He is an ethnic Russian who has incorporated a mild dose of nationalist sloganeering into his patter.
The song – supposedly about lost love – also signposts Sumner's emergence as a vocalist, reputedly starting to enjoy singing after a mild dose of acid and a snowball down his shirt (the latter courtesy of Hook).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com