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A negative outcome that included persistent or new-onset medication overuse was present in 34% of migraineurs and was associated with baseline poor orbitofrontal task performance, and with mild dorsolateral dysfunction, higher rates of depression, anxiety and neuroticism-anxiety traits.
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Dorsolateral dysfunction was present in both groups of migraneurs, who also had higher rates of anxiety as compared to controls.
CASS indicated mild autonomic dysfunction.
Laboratory examinations revealed general inflammation and mild hepatorenal dysfunction.
Blood tests revealed thrombocytopenia and mild liver dysfunction.
To some extent, this may have produced skeletal muscle damage leading to mild renal dysfunction.
We hypothesized that patients with mild olfactory dysfunction (hyposmia) would benefit from ESS, whereas patients with severe olfactory dysfunction (anosmia) would not.
Conclusion: Part of the pathogenesis of recurrent vertigo or dizziness with brainstem infarction might be due to mild autonomic dysfunction.
The CASS may be a sensitive tool for assessing mild autonomic dysfunction in patients with brainstem infarction.
Table 1 Clinical characteristics of subjects Classification Age/Sex Symptoms Living arrangement DRS FDG-PET PiB-PET Tau-PET Normal 54/F None Independent 143 (94%) Clinically-Mild AD 78/M Mild memory dysfunction.
Laboratory examinations revealed general inflammation (leukocyte count, 15,700/μl; C-reactive protein level, 16.2 mg/dl), mild liver dysfunction (total bilirubin, 2.97 mg/dl; direct bilirubin, 0.81 mg/dl), and mild renal dysfunction (creatinine, 1.40 mg/dl).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com