Suggestions(1)
Exact(4)
Contrary to the findings by Mairal et al (2000) that tumours with amplification of N-MYC show mild differentiation, all three tumours studied here were poorly differentiated.
Current data show mild differentiation only of the Monterey population from others in the data set.
In G2 lesions, the cell arrangements were irregular, with mild differentiation and minimal nuclei atypia.
Smg6-mutant ESCs are completely blocked for differentiation, even at early passages, which is in contrast to the mild differentiation defect seen in telomerase-knockout ESCs, which appears only at very late passages (more than 67 passages) (Pucci et al, 2013).
Similar(56)
We propose that the pattern of distribution of haplotype diversity in the C. mendocinus species complex corresponds to a scenario of mild local differentiation with subsequent expansion to the current distribution ranges.
The lack of any significant effect of GATA-1 deficiency on platelets is consistent with a previous study demonstrating a mild megakaryocyte differentiation defect in the absence of GATA-1 (Gutierrez et al, 2008).
According to a recent study, during the period of de-differentiation there can be temporary expression of exogenous Oct4, which inhibits the transcription of Sox2, permitting subsequent mild activation of differentiation markers.
This is further confirmed by the observation that wild-type HOXA9 had only a mild effect on differentiation in spite of containing both the homeodomain and a transactivating domain.
Expression of rok CAT alone in clones did not substantially affect clone size compared with wild type, but showed mild disruption to differentiation, with Elav-positive cells detected in basal sections (arrows, Fig. 6A-Aii,B-Bii).
An isolated NUP98 moiety (NUP98ΔC) that comprises the FG repeat region of NUP98 caused a mild disruption of myeloid differentiation, but did not have a significant effect on erythroid differentiation or proliferation (Fig. S1).
In the case of bare PPEES nanofibers, the color change was mild, reflecting the low differentiation of MG-63 cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com