Suggestions(2)
Exact(2)
Although the higher levels of prenatal mortality seen among domesticated foxes relative to control, farm-bred animals indicates mild deleterious effects (L. Trut, personal communication), this is not to the extent that might be expected for disabling mutations in a large and early-acting GRN.
For instance, the wRi and wHa infections in D. simulans are restricted mostly to gonadal tissues (Binnington and Hoffmann 1989; Correa and Ballard 2014), have mild deleterious effects (Hoffmann et al. 1990; Turelli and Hoffmann 1995) and cause mid- to low-level viral blockage (Osborne et al. 2009).
Similar(58)
It is probable that the methylphosphonate anion has a lower destructuring ability than the acetate on the yeast cell wall polysaccharides, which could explain the milder deleterious effect of [Emim][MeO(H PO2].
This is most likely explained by the short follow-up, which may not reveal the deleterious effects of mild vitamin D insufficiency, thus leading to underestimation of the impact of vitamin D on the risk of diabetes; however, the presence of a vitamin D level threshold above which there is no impact on the development of diabetes cannot be excluded.
It is possible secondary deleterious effects resulting from ubiquitous mild uncoupling activity may be overcoming any beneficial tissue-specific effects of decreased ROS production, providing an explanation for the lifespan effects.
A growing body of research suggests that subconcussive head impacts or repetitive mild Traumatic Brain Injury (mTBI) can have cumulative and deleterious effects.
Cold shock causes severe pathologies in the mammalian brain [2], whereas mild cooling (to 32°C) can support survival and delay the deleterious effects of infarction [3].
This would indicate that negative selection would be very effective in eliminating even mild deleterious variants.
I've gone to bed angry loads of times, with no particular deleterious effects.
Several studies also contradict the conclusion that these chemicals have deleterious effects.
Are other pupils in the same schools hermetically sealed from the deleterious effects of such teachers?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com