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This observation suggests that the mutation may cause a mild delay in G1, consistent with the increased doubling time and profile of DNA replication observed for elm1T551A.
At a pre-school age, she showed a mild delay in developmental milestones.
Finally, only the Neapolitan siblings had mild delay in reaching the child developmental milestones [ 3, 4, 52].
When cells are released at 32°, the entry into S phase was advanced in both ERG26 and erg26 cells, but the erg26 cells still exhibited a mild delay in S-phase progression compared with the ERG26 control.
Compared with OLIG2, OLIG1 plays a secondary and nonessential role in oligodendrogenesis as OLIG1 null mice lines have shown only a mild delay in oligodendrocyte differentiation and maturation without long-term effect [ 137].
Importantly, teriflunomide treatment in this viral model of MS only resulted in a mild delay in the production of antiviral antibodies and was associated with a transient, non-significant increase in viral load in the CNS 30 days post-infection.
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During the experiment, there were no signs of infection except for a few mild delays in wound healing due to self-extraction of the operation suture, requiring no treatment.
The prevalence of SLI has been estimated at around 7% (Tomblin et al., 1997), although this will vary with both the diagnostic criteria and children's age: Long-term language impairments that persist into adulthood are less common than milder delays in preschoolers, which may resolve with time (Bishop & Adams, 1990).
The defects in looping ranged from a mild delay to a completely unbent tube (Fig. 5D).
Thus, a mild heterochronic delay in sympathetic reactivity, caused by delayed adrenal gland maturation, can have important life-long effects at higher cognitive levels, via a simple prolongation of a sensitive period for positive contact with humans.
A single individual was described with mild developmental delay in motor and language.
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CEO of Professional Science Editing for Scientists @ prosciediting.com