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The proportions of immunopositive NP cells in each grade grouping (that is, 0 to 3 non-degenerate, 4 to 6 mild degeneration, 7 to 9 moderate degeneration and 10 to 12 severe degeneration) were counted and compared for statistical significance using the Mann-Whitney U test.
The grading system generates a score between 0 and 12: a grade of 0 to 3 represents a histologically normal (non-degenerate) disc grades of 4 to 6 indicate mild degeneration, grades 7 to 9 moderate degeneration and grades 10 to 12 severe degeneration.
The grading system generates a score of between 0 and 12: a grade of 0 to 3 represents a histologically normal (non-degenerate) disc, grades of 4 to 6 indicate mild degeneration, grades 7 to 9 moderate degeneration and grades 10 to 12 severe degeneration.
The histopathological examination of the kidney treated with ink extract revealed mild degeneration in renal tissue architecture, as compared to BDL groups.
There was moderate neutrophil infiltration, moderate edema, mild degeneration, and atrophy in the CS-only group.
Lesions were characterized by mild degeneration and early squamous metaplasia confined to specific regions of the transitional and respiratory epithelia of the nasal passages and the respiratory epithelium of the trachea and major bronchi.
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However standard control and test group showed significant changes in surface syncytium, tegument cells and rupture of parenchymatous cell, mild vacoular degeneration of teguments, degeneration of testes and Vitelline gland (Fig. 6).
*Standard of classification and score for the degree of lipid deposition: +, mild fatty degeneration, fatty hepatocytes occupy 30-50% of the hepatic parenchyma; ++, moderate fatty degeneration, fatty hepatocytes occupy 50-75% of the hepatic parenchyma; +++, severe fatty degeneration, fatty hepatocytes occupy > 75% of the hepatic parenchyma.
The classification and degree of fatty deposition used was as follows [ 22]: +, mild fatty degeneration, fatty hepatocytes occupy 30%-50 30%-50e hepatic parenchyma; ++, moderate fatty degeneration, fatty hepatocytes occupy 50%-75% of the hepatic parenchyma; +++, severe fatty degeneration fatty hepatocytes occupy > 75% of the hepatic parenchymoderate
e-h Standard control showing mild vacoular degeneration of Anterior sucker (As) 4x (e), Disrupted and detached Sub syncytium (Ss) 10x (f), Degeneration of Testes (Td) 10x (g), Degeneration of Vitelline gland (Vgd) 4x (h).
Moreover, the tensile pre-strained cells may further be utilized in either cell therapy to treat mild disc degeneration disease, or the development of a disc construct for total disc replacement.
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