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Electroencephalographic (EEG) results showed poor alpha waves and mild cortical dysfunction.
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The 46-year-old man reported by Liu et al. (2011), who presented with an acute depressive episode, mild diffuse cortical dysfunction on EEG, and hypothyroidism with the presence of thyroid antibodies in both serum and CSF, was successfully treated with thyroid hormone replacement and methylprednisolone.
On the 12th day, an abnormal EEG was recorded, with mild-to-moderate cortical dysfunction without epileptic findings.
A slowing of the normal alpha rhythm with appearance of theta activity occurs in patients with no evidence of encephalopathy or with mild to moderate encephalopathy (confusion, delirium) and reflects cortical dysfunction.
Laser evoked potentials (LEPs) have confirmed this cortical dysfunction also in pain elaboration [3, 4].
Schizophrenia pathology is introduced using quantitative human imaging data on striatal hyperdopaminergic activity and cortical dysfunction.
These findings suggest that the interictal cortical dysfunction induced by migraine prevents the cortical changes induced by tonic painful stimulation both during pain and after pain ends.
Overall, the disease-related interictal cortical dysfunction in migraine prevents the cortical changes induced by tonic painful stimulation both during pain and after pain ends.
Neuropsychological exams combined with imaging methods showed the existence of cortical dysfunction associated with impaired cognition [7].
There is increasing evidence that brainstem, as well as cortical dysfunction, are basically involved in the complex pathophysiology of migraine.
It is unknown if cortical dysfunction is present at rest, i.e. in the absence of any external stimuli.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com