Together, these mild effects imply a modest contribution of CS-complex spikes to conditioned behavior on a trial-by-trial basis.
However, in this model, the disease is again relatively mild, and the contribution of radiation-induced tissue injury and MPO+ T cells is unclear.
Again, CaV1 channels are responsible for a larger fraction of Ca2+ influx following mild stimulation, whereas the contribution of CaV2 channels predominated with more intense stimuli.
The disaggregated costs of "HCV without liver disease" were estimated by taking into account the relative contribution of mild (F0, F1), moderate (F2), and severe (F3) to the total HCV-related cost reported in Davis et al. [ 50].
The prediction model was not valid in the MILD sample except for the contribution of pain-related disability.
However, it was also demonstrated that the Na+ transport activity of OsHKT2 1 is rapidly down-regulated in intact rice roots even upon a mild salt stress, suggesting that the contribution of OsHKT2 1 to toxic Na+ influx during salinity stress is little (Horie et al. [2007]).
Indeed, the juvenile form of the disease in patient #26 (Table 1), carrying the large 30kb deletion (c.1161+6532_polyA+9kbdel) on one GALC allele, may have been consequent to the contribution of the putatively milder p.G286D (G270D) lesion on the second allele.
However, recent studies have outlined a potential contribution of systemic and local mild chronic inflammation in initiating the neurodegenerative cascade observed in AD [ 17, 18].
Interestingly, anti-dsDNA autoantibodies of the IgE isotype are elevated in active versus mild disease in SLE sera, suggesting a contribution of the type 2 response in active nephritis (Charles et al., 2010).
Yet, studies of mouse lines lacking Dp427 or all dystrophins only showed mild cognitive impairments and failed to unveil the specific contribution of Dp71 to neuronal function and to the genesis of MR [12] [14].
