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In contrast, the infected black-footed ferret in our study had relatively mild clinical illness, consisting only of lethargy.
Despite the rapid and widespread dissemination of the virus, thus far most of those infected have suffered mild clinical illness with the overall mortality rate at less than 1% (approximately similar to seasonal influenza) [ 1, 2].
Furthermore, it must be considered that autoimmune diseases could be undiagnosed before pregnancy because the mild clinical illness that could be modified by the occurring pregnancy that interferes with the immune system.
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A less severe manifestation, primary cutaneous melioidosis, causes skin lesions and milder clinical illness.
Because all patients infected with serogroup Canicola were observed before 1967, dialysis and ICU treatment were not available for these patients, but absence of these treatments does not indicate milder clinical illness.
That mild initial clinical illness progresses to severe sepsis and death despite appropriate clinical care highlights host responses to sepsis that differ between survivors and non-survivors.
At 6 h septic animals displayed only mild clinical features of illness.
At 6h the animals manifested only mild clinical features of illness, however significant differences were seen in IL-6 and all lipid measurements between predicted survivors and non-survivors.
Dobrava-Aa may induce a similarly mild clinical course of illness to that of Puumala virus (6 ).
The premises contained 6,000 breeding ducks ≈60 weeks of age housed in 3 sheds; the ducks showed only mild clinical signs of illness.
We could not confirm whether the patient's influenza vaccination and high levels of vaccine-derived subtype H1N1 neutralizing antibody influenced his relatively mild clinical course of illness.
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