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In order to evaluate the cardioprotective effect of the mild chronic exercise training protocol, I/R experiments were performed.
In order to identify functional gene sets correlated with mild chronic exercise training, we applied GSA analysis.
In order to identify functional gene sets correlated with the mild chronic exercise training, we applied GSA analysis.
Our study aims at investigating the cardioprotective effect of mild chronic exercise training and the gene expression profile changes at 48 hrs after the exercise cessation.
It might be hypothesized that the cardioprotection resulting from the adaptation to mild chronic exercise training is the result of a summation of several second windows of protection similar to what observed during ischemic preconditioning.
However, the experimental design of the Freimann's group differed from ours as we evaluated the gene expression profiles that characterized animals after the mild chronic exercise and, in a different set of rats trained in parallel using an identical training protocol, we determined the cardioprotection by measuring the extent of the injury caused by ischemia/reperfusion experiments.
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In conclusion, mild aerobic chronic exercise training, at a level that does not induce cardiac hypertrophy, was found to induce cardioprotection toward I/R events.
His diagnosis, records show, was mild chronic depression accompanied by defiant and negative behavior.
CHB-M, mild chronic hepatitis B; CHB-S, severe chronic hepatitis B; ACLF, acute-on-chronic liver failure.
To accomplish this, the results were divided into single sessions of acute exercise and chronic exercise, based on periodicity.
Acute exercise is a small source of oxidative stress, while chronic exercise elicits protective adaptations against oxidative damage.
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