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In addition, we found that the astrocytic mutation instigated neuronal modifications: 1) neocortical pyramidal neurons exhibit mild but significant changes in their membrane properties, and 2) the mutant mice display a distinct behavioral phenotype.
Our data also do not indicate cardiac dysfunction after radiation alone or in combination with lapatinib, in contrast to the mild but significant changes in cardiac function after lapatinib alone (Fig. 9).
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Specifically, dietary deficiencies of iron, zinc, iodine, selenium, copper, manganese, fluoride, chromium, and molybdenum are associated with mild to significant changes in neuronal function that can lead to poor health and adverse effects on behavior and learning [ 6].
The treated segments, however, in terms of both perfusion and resistance, showed a mild but significant improvement, 11 and 15 %, respectively, whereas, no change could be observed in the remote segments.
The treated segments, however, showed in terms of both perfusion and resistance a mild but significant improvement, by 11 and 15 %, respectively, whereas no change could be observed in the remote segments.
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