By contrast, much milder trabecular bone damage (−16% in vBMD, −19% in BV·TV−1, −6% in Tb.N, −13% in Tb.Th, +7% in Th.Sp, and +69% in SMI) was detected in the subchondral area, implying that the extent of trabecular bone loss induced by SCI is site-specific even within the same bone.
The histology of ankle joints from CIA mice showed severe proliferation of synovium with significant inflammatory cell infiltration, pannus invasion, cartilage damage and bone resorption compared with normal mice, while joints from THR0921-treated mice showed mild synovial hyperplasia with less inflammatory cell infiltration, no pannus formation, and little cartilage and bone damage.
"There's some bone damage and some ligament damage," Nady said.
There is no bone damage; we knew that straightaway after the game but there is ligament damage.
Chronic exposure to cadmium has been linked to kidney, liver, and bone damage.
There was a mild bone activity on the condyle head in the three-phase bone scan.
Mild bone abnormalities were frequently observed, including changes of shape and contour of bone surface, and sclerosis of bone marrow.
In the area from the left leg to the foot, plain X-rays revealed mild bone atrophy and magnetic resonance imaging (MRI) revealed mild bone and muscle atrophy.
Doctors treat severe bone damage and cancer by replacing the affected bone with sections of bone from a cadaver.
The bone damage and erosion score was graded from 0 to 5 (0 = normal; 1 = minimal loss of cortical bone at a few sites; 2 = mild loss of cortical trabecular bone; 3 = moderate loss of bone at many sites; 4 = marked loss of bone at many sites; 5 = marked loss of bone at many sites with fragmenting and full thickness penetration of inflammatory process or pannus into the cortical bone).
