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Discussion In this preliminary study from selected cohorts of non-immunocompromised patients, sepsis resulted in mild alterations in platelet counts, making it unlikely to become associated with the development of nosocomial infections.
Both male and female transgenic mice displayed mild alterations in the circadian activity patterns, but no deficits in PPI.
Notably, only mild alterations in dopaminergic neurotransmission have been observed, but no degeneration of dopaminergic neurons, which might be explained by functional redundancy or compensatory mechanisms [6], [7], [8], [9].
In contrast, 129S1/SvImJ mice had delayed transition to decompensated heart failure, with relatively mild alterations in histology and markers of hypertrophy at five weeks post-TAC and preserved systolic function until eight weeks post-TAC, suggesting that 129S1/SvImJ genetic modifiers might protect against the earlier and more severe pathological changes seen in C57BL/6J mice [39].
Mild alterations in the liver function tests are common, but hepatic failure is distinctly rare.
However, more recent attempts to replicate these findings have found mild alterations in bone metabolism without any adverse health effects.
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He rarely drank; maybe he so enjoyed being exactly as he was that he didn't want even the mild alteration in mood brought on by a glass of Chardonnay.
Oleate represents a mild alteration in carbon source.
Surprisingly, they did not cause significant alterations in the protein profile, and caused only very mild alteration in the phenotype of the P25-expressing transgenic plants.
This mild alteration in nerve function was accompanied by a poorer performance of the JAM-C SC KO mice in a behavioral test of muscular strength (Fig. 5 A ).
Exposure of mice to a higher dose of BPA (100 µg/kg/d) during days 9 to 16 of pregnancy produced a different phenotype in the male offspring at 6 months of age, characterized by glucose intolerance but normal insulin sensitivity and a mild alteration in β-cell function (Alonso-Magdalena et al., 2010).
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