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For example, the presence of a provisional matrix signals the transition of basal keratinocytes from a sedentary to a migratory phenotype [8] [10], [23] [24], while the presence of a mature BM signals the transition of keratinocytes from a migratory to a sedentary phenotype [9] [10], [12], [23], [32].
If CACN-1−binding partners are required to orchestrate the transition of the DTC from a migratory to a stationary cell type at the end of larval morphogenesis, then depletion of these proteins should also result in the overshoot phenotype.
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The major defect we observed, failure to stop migrating at the end of L4, is consistent with failure of the DTC to convert from a larval (migratory) to an adult (stationary) phenotype.
Here, we show that MT depolymerization converts T cells from a lamellipodial/uropod migratory phenotype to a blebbing migratory phenotype, correlating with increased RhoA/ROCK activity.
MT depolymerization induces high levels of RhoA/ROCK activity at multiple points of the cell cortex, shifting cells from a lamellipodium/uropod migratory polarity to a ROCK-mediated membrane blebbing morphology with low migratory persistence (Figure 10).
Of the hundreds of fish species in the river, 87percentt are migratory, according to a 2006 study.
Billed as "The Flight of Hope," Mr. Putin's September expedition was part of an ambitious plan to lead the cranes on their first migratory flight to a nature reserve to the south, from where they were to journey eventually to Uzbekistan.
The initial response of migratory cells to a migration-promoting agent is to polarize and extend protrusions.
Note the rapid morphological changes in MEC1 cells from a polarized migratory phenotype to a rounded morphology.
These cells also produce TGF-β1 that stimulates or activates the transition of fibroblasts from a "replicative and migratory" phenotype to a "matrix synthetic" myofibroblast phenotype [ 24].
The migratory event amounts to a traumatic experience, and like other experiences of anomaly and existential insecurity, it increases receptivity to religious belief.
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