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Furthermore, an immunofluorescence assay confirmed the co-localization of uPAR and integrin β1 at the migratory front of the irradiated cells (Fig. 3C).
We have previously demonstrated colocalization of CD44 and MMP9 at the migratory front of osteoclasts [ 20].
The neuroectodermal networks of the gut remain in a state of flux long after the migratory front of NC cells has passed through a given segment of the intestine.
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One of the most interesting aspects of the Young et al. paper is the suggestion that all the information required to drive key events in gut colonization by NCs and neural circuit development, such as the effective rostrocaudal advance of the migratory front and the organization and direction of neurite outgrowth, is intrinsic to ENCCs and largely independent of the polarity of gut mesenchyme.
Following identification of the migratory front in the olfactory bulbs the distance from the frontal cortex to the migration front was measured (Figure 8B).
Although the migratory pattern of any given ENCC is unpredictable, as a population follower cells behind the migratory front are likely to leapfrog the ones ahead of them and form the new leaders.
"We are at the front of the migratory wave of wolves," Jansman said.
The assembly of FAs in migratory cells generally occurs at the cell front of the moving edge, while disassembly occurs both at the leading edge, where it accompanies the formation of new protrusions and at the cell rear where it promotes tail retraction.
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