Sentence examples for migratory defects of from inspiring English sources

In these patients, high CD49d levels appear to overcome some of the migratory defects of the CLL cells [ 96].

They showed that the migratory defects of PTP-α-/ fibroblasts are associated with altered cell morphology at the leading edge of migrating cells.

This provides a new molecular insight into the known migratory defects of Bra knockout cells (Yanagisawa et al., 1981) and agrees with the EMT-promoting role of BRA in human cancer samples (Fernando et al., 2010).

Furthermore, the migratory defect of UBCs was completely rescued in the transiently MEKi-treated cerebella of G-responders, which contained a relatively normal number of glial cells.

The migratory defect of N-APC-expressing cells was observed regardless of the point of origin of cells within the primitive streak, which affects the exact direction of the migratory path (Yang et al., 2002) (data not shown).

Works in zebrafish have brought insight into defects in cloaca malformation by showing a migratory defect of cells that form the cloaca opening, preventing programmed cell death of ectodermal cells (Slanchev et al., 2011).

Compensation by other FLN isoforms is a likely explanation for the lack of major migratory defects in most tissues of single knockout animals.

The failure of preplate neurons to polarize in the absence of RELN or SFK signaling could be a consequence of the defects in radial glial morphology previously described in reeler or a secondary consequence of the migratory defects observed in neurons of the reeler ectopic cortical plate.

Mice lacking Dicer exhibit several functional and molecular alterations of neurogenesis that include the following: the mis-expression of specific RG cell markers (Sox9, ErbB2 and Nestin), migratory defects, and the derangement of the cortical plate and the hippocampus.

Obviously, this does not exclude that hnRNPH might also affect other targets important in GBM biology, in particular some involved in the modulation of cell motility, as suggested by the only partial rescue of migratory defects in hnRNPH-ablated T98G cells.

Moreover, an evident accumulation of CB-positive precursors along the migratory pathway as a consequence of migratory defects has not been detected by us.