Importantly, this modulation in signal transduction directly affected the migratory ability of endothelial cells.
Accordingly, EVL restricts the migratory ability of MCF10A and untransformed ER-Src cells, as well as SUM159 breast cancer cells12.
In this condition, Zeb1 restored the migratory ability of the cells regardless the presence of AA6 (Fig. 7b).
The regenerative abilities of sponges, their lack of a central coordinating organ (brain), and the peculiar migratory ability of cells within the organisms combine to make it somewhat difficult to define sponge individuality.
This EMT is marked by increased expression of the transcription factor Zeb1, and Zeb1 is required for the enhanced migratory ability of DKAT cells in the mesenchymal state.
Doxorubicin-induced cytoskeleton remodelling suggests that doxorubicin may alter the migratory ability of EPCs.
However, incubation of cells with NSC23766 suppressed the enhanced migratory ability of SSc fibroblasts to that of controls (Figure 4).
Migratory ability of BCPAP, 8505C, CGTHW-1 and ML-1 cells was also assessed by a scratch wound assay.
Our previous research also indicated that PRL-3 with inactive PTP domain reduced the migratory ability of tumor cells [3].
The migratory ability of tumor cells was assayed in Transwells (Costar, Cambridge, MA) as reported previously [39].
Moreover, the addition of estradiol along with 25 µM DIM (striped bars) did not improve the migratory ability of thyroid cells, signifying the antiestrogen like ability of DIM.
