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Experimental evidence shows that disrupting this balance can induce aberrant cell proliferation, adhesion, function and migration reviewed by Barcellos-Hoff (1998).
In fact, in line with this notion, K+ channels have been shown to be relevant for tumor proliferation and migration (reviewed by Beug).
Src family members have been implicated in numerous biologic activities, including proliferation and migration (reviewed by Brown and Cooper, 1996; Thomas and Brugge, 1997).
Yet, other TGF β family members (such as BMP), Snail family members, FGFs and Wnt play a role in embryonic single cell migration (reviewed by Locascio and Nieto, 2001).
However, activities in addition to those mediated by E-Cadherin, such as via integrins as well as via a cytokine-based adhesion system are known to be involved in the interactions of mouse PGCs with their surrounding somatic cells and adjacent PGCs during migration (reviewed by De Felici, 2000).
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Previous studies have shown that the effect of cAMP on migration of cancer cells is ambivalent — migration of some cell types is inhibited by cAMP increase whilst other cell types require cAMP signalling for efficient migration (reviewed in [19,20]).
Recent evidence suggests that selective AQP participate in angiogenesis, cell migration and metastasis (reviewed by [ 8]).
A deterministic role for the transmembrane subgroup of MMPs (MT-MMPs) has been revealed for cancer cell transmigration through stromal and basement membrane matrices, which pose protease-dependent barriers to cell migration in vivo (reviewed by [ 101]).
Ukraine's border agency said that an application for asylum was being reviewed by migration authorities.
Similarly, mutations have been shown to link to epilepsy in genes that regulate neuronal proliferation, migration and circuit remodeling (reviewed by Bozzi et al., 2012).
Mammalian screens have largely focused on the field of cancer biology and have been used to identify genes involved in cell proliferation, survival, invasion and migration, and responses to drugs (reviewed by Simpson et al., 2012).
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