We found that a single mutation allows Mt-trHbN to acquire ligand migration rates comparable to those observed for Mt-trHbO, confirming that ligand migration is regulated by the internal tunnel architecture as well as by water molecules stabilized in the active site.
Nguyen-Ngoc, K.V. & Ewald, A.J. Mammary ductal elongation and myoepithelial migration are regulated by the composition of the extracellular matrix.
Provenzano, P. P., Inman, D. R., Eliceiri, K. W., Trier, S. M. & Keely, P. J. Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization.
Recent advances in intravital imaging and the development of an in vivo invasion assay have provided new insights into how cancer cell migration is regulated by elements of the local microenvironment, including the extracellular matrix architecture and other cell types found in primary tumors.
Vascular smooth muscle cell (SMC) migration is regulated by cytoskeletal remodeling as well as by certain transient receptor potential (TRP) channels, nonselective cation channels that modulate calcium influx.
These findings thus confirm that SMC migration is regulated by LRP1 through the PDGFRβ-dependent PI3K pathway.
Previous studies have shown that cell migration is regulated by cell adhesion and changes in transmembrane flow and that the integrin/channel complex contributes to this role.
Earlier studies have shown that S1P-induced EC migration is regulated by several distinct signaling pathways and depends on the cell type, type of S1P receptor, and concentrations of S1P.
Tracheoblast migration is regulated by mitogen signaling and topographical guidance [ 12, 18].
How amoeboid migration is regulated by extracellular signals and sustained over time by transcriptional changes is not fully understood.
