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When the migration probability is large (e.g., m > 0.3) the differences in the release threshold for the three proportions of release area are very small.

When the migration probability is small, there are some differences in the release thresholds between 1/16-, 1/4-, and full release (Fig. 3A,B).

For example, when the migration probability is 0.2, the critical fitness cost is between 0.03 and 0.04 for both-sex release (Fig. 5A), and between 0.01 and 0.02 for only-male release (Fig. 5B).

For example, when there is no fitness cost associated with the transgene, the migration probability is 0.3 and 1-day-old adults are released, male-only release requires approximately 110% more engineered insects than both-sex release when β = 1, while it requires 80% more engineered insects than both-sex release when β = 4.

When the migration probability is greater than the optimal value, the transgenes spread quickly into many patches, which causes the ratio of released individuals to wild individuals in the release area to drop quickly after the release and makes it relatively difficult for transgenes to increase in frequency in the release area.

When the migration probability is smaller than the optimal value, the outward expansion of the transgenes is slow, which makes it relatively difficult for the transgenes to reach a frequency of 80% across all patches in 3 years (as required by our practical criterion).

Similar(54)

The only significant associations between anatomic factors and device migration probability were the protective effects of longer necks (odds ratio [OR] = 0.71 for each additional 5 mm, p = 0.045) and longer overlapped portions of neck and device (OR = 0.56 for each additional 5 mm, p = 0.003).

If both the release area and migration probability are small, the transgenic individuals may spread over only a part of the entire area in 3 years and may never reach a frequency of 80% even if a large number of insects are released.

This is at least partially because at low migration probabilities the patchy releases cause a faster spread of the transgenic alleles into the nonrelease patches, but when the migration probabilities are high the invasion into the nonrelease patches is not a major limitation.

Note that the daily migration probability, m, is assumed to be independent of sex, age, and genotype.

The grain boundary atom is attempted to re-align with neighboring grains to represent the grain boundary migration; the attempt probability is defined by the grain boundary migration coefficient.

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