Sentence examples for migration of microglia from inspiring English sources

However, the potential migration of microglia progenitors in response to chemotactic factors cannot be ruled out from this study.

PTx significantly inhibited the migration of microglia with and without IFN-γ stimulation (Fig. 10).

The migration of microglia in vitro was determined by using Transwell (pore size 8-µm 8-µmning, VWR, San Dimas, Corning

However, male M5R−/− mice did not show migration of microglia (Iba-1 or Mac-2 positive cells) in cortex and hippocampus (Figure S4C).

The observed migration of microglia towards the growing sprouts suggests that their position near endothelial tip-cells could result from attractive cues secreted by the vessels.

Centrally administered PTx abrogated migration of microglia in EAE mice, limiting the inflammatory cytokine milieu to the brain and prevented dissemination of demyelination.

The early upregulation of TNF-α, before the migration of retinal microglia and infiltration of macrophages, suggests that innate immunity could cause oxidative stress during early EAU.

However, contrary to earlier observations, later studies revealed that during the early phase of EAU (postimmunization day 5) retinal ONOO− initiated damage occurred before there was any histologic or immunohistochemical evidence of macrophage infiltration or migration of retinal microglia [6, 15].

We speculate that the migration of retinal microglia into the subretinal space in early stages of the disease induces significant changes in RPE cells that perpetuate further microglial accumulation, increase inflammation in the outer retina, and fosters an environment conducive for the formation of neovascular changes responsible for much of vision loss in advanced AMD.

Stromal cell-derived factor-1 has also been shown to induce migration of brain microglia and astrocytes (Tanabe et al, 1997).

VEGF also acts as a proinflammatory cytokine [ 47] and promotes migration and proliferation of microglia in vitro [ 48].