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GSK-3 activity is critical for the radial migration of later born, Cux1-expressing neurons in all regions of cortex, and for radial migration in the hippocampus.
Cerebral PNH in FLNA patients is caused by impaired migration of later born neurons due to disrupted cell adhesion and abnormal ventricular ependymal function [ 15].
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The first FBM neurons reach their target by 24 hpf (Fig. 1G) and the migration of later-born FBM neurons is complete by 48 hpf (Fig. 1B).
This failure has been attributed to defects in the cessation of the migration of later-generated neurons destined for the cortical plate (Caviness 1982; Goffinet 1984).
We therefore aimed at introducing the CFP stem with its purportedly superior properties in a prospective cohort study, and hypothesized that (1) loss of proximal periprosthetic BMD is reduced compared to conventional implants, and (2) early implant migration (suggestive of later loosening) is small.
Furthermore, migration is predictive of later mechanical loosening (Karrholm et al. 1994, Ryd et al. 1995).
In addition to existence of migration (see later) they expect also similar results in Evolution Canyon as they got in their Australian and American researches.
These dACs enter the last phase of migration much later than other dACs, and, rather than flattening their cell bodies, they send out a basal process through the proto-IPL to the plane where other dACs have stratified earlier and then rapidly squeeze through the proto-IPL (supplementary material Fig. S5).
That reflects the formation of OWC and migration of POWC occurred much later.
This migration of seed capital to later, larger deals has created a bifurcation in the market with Seed rounds under $1million (i.e. pre-seed) valuations relatively stable while seed rounds of more than $1 million are undergoing significant inflation.
The subgenus Leishmania comprises species limited to the midgut and foregut of the sand fly, whereas the subgenus Viannia includes species that develop a prolonged phase in the hindgut with later migration of flagellates to the midgut and foregut of the vector's alimentary tract.
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