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Hence, the study of the mechanisms controlling the migration of infected cells and the potential role of migrating and non-migrating DC in the development of lesions is important to understand the pathogenesis of inflammatory diseases.
Beyond immune evasion, HCMV controls the motility and differentiation of infected cells in order to promote virus dissemination, and infection of endothelial cells can promote transendothelial migration of infected monocytes by increasing the permeability of the endothelium (Bentz et al., 2006).
We found that F11 promotes the spread of infection not only by enhancing viral release but by also stimulating the migration of infected cells after their loss of cell-cell adhesion.
But increased migration of infected people into urban areas in Mexico and Central and South America as well as into the United States and other countries, particularly those in Europe—has facilitated the spread of the disease.
MVA inhibited directional migration of infected and bystander immature DC subsequently matured with LPS for 24 h toward a gradient of CCL19 chemokine [43].
Connectivity in the epidemiological sense is determined by the migration of infected or infectious hosts, which is affected by the average age of the infected or infectious population, the distance separating sub-populations, landscape features that inhibit or direct movement, seasonality in birth rates, juvenile transmission, or contact rates, and the behavior of the hosts or vectors.
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Our molecular findings suggest that HHV-8 has been introduced in the Ni-Vanuatu populations by different migrations of infected persons.
Accordingly, migration out of infected demes will drive up infection frequency in adjacent demes very effectively and is more likely to bring infection frequency in the range of positive selection for infection.
The antibody against p37 protein of Mycoplasma hyorhinis could inhibit the migration of the infected cells.
To examine the influence of the Golgi apparatus in the centripetal migration of SCVs, infected cells were treated with BFA at 15 min p.i. and fixed 1 h 45 min later.
It allowed us to show an endemic mode of TB transmission in French Guiana associated to low local transmission of the disease, with both resurgence of old spatially restricted genotypes (endemic to French Guiana), and an importation of new TB genotypes by migration of TB infected people from high-incidence countries.
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