Sentence examples for migration of granule from inspiring English sources

Furthermore, both inward migration of granule cells into the inner granule cell layer (IGL) and outward migration of GABA interneurons into the molecular layer (ML) were arrested, disrupting layer and lobular morphology.

A previous study suggested that the delayed migration of granule cells in the En2-cre Jag1f/f En2-cre Jag1f/fconditionalellum might be due to the mis-organized Bergmann glial fibers [23].

A plausible explanation for the defects in cerebellar foliation of the PEX13 brain mutants is the impaired migration of granule cells and abnormal Purkinje cell development.

An abnormal migration of granule neurons into the molecular layer resulted in the formation of an additional fragmentary granule cell layer (Fig.  3e).

The delayed disappearance of the EGL together with the delayed formation of the IGL is consistent with a defect in migration of granule cells in the mutant animals.

Conversely, impaired migration of granule cells might lead to reduced outgrowth and irregular alignment of Purkinje cell bodies, because migrating granule cells facilitate these developmental milestones in Purkinje cells (Baptista et al., 1994; Salinas et al., 1994).

These results are in line with a previous in vitro study [19] demonstrating that SRIF-28 increases the migration rate of granule cells near their birthplace, but decreases it near their final destination in the IGL.

Bergmann glia expressing glial fibrillary acidic protein have been previously identified in MLH and were shown to have disorganized radial fibers [ 11] which may be responsible for the migration defect of granule cells.

Bagri, A. et al. The chemokine SDF1 regulates migration of dentate granule cells.

In addition to the present results, it has been reported that in the CNS, in addition to CR cells, the migration of cerebellar granule precursors34, cortical interneurons23, microglia45, neural precursor cells46, and certain brain tumour cells33 is also dependent on CXCL12/CXCR4 signalling.

The radial fibers of Bergmann glia also act as essential guide rails for the migration of cerebellar granule cells [4], [5].