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Interestingly, blocking PIM kinases with small-molecule inhibitors was able to impair the migration of acute myeloid leukaemia cells by downregulating the CXCR4 chemokine receptor at the cell surface (Grundler et al, 2009).
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A growing body of studies has demonstrated that EGF can accelerate reepithelialization by increasing the proliferation and cell migration of keratinocytes in acute wound [ 23– 27].
The data collectively indicate that P-selectin and ICAM-1 each may have a role in neutrophil migration during early stages of acute bacterial peritonitis, but at later stages alternative pathways are recruited to mediate neutrophil migration.
Consistent with their in vitro migration to inflammation (CCL4, CXCL12) and lymph node expressed chemokines (CCL19, CXCL12) competentpeTent T cells are licensed for migration into both, sites of acute inflammation and lymph nodes.
CXCR2 was shown to be important for neutrophil migration in a model of acute gout [ 18].
"The resulting predictions of migration during acute events would enable better planning by all levels of government officials, from local municipalities to international bodies, with the potential to save millions of human lives," note the researchers.
Intraoperative TEE is a useful monitor since the risk of acute PTE by migration of the tumor has yet to be determined in the case of ACC.
Leukocyte migration is an important step in several types of acute and chronic inflammation as well as autoimmune diseases.
Every episode of acute disc displacement leads to further migration of the nucleous pulposus posteriorly and worsening of the annulus fibrosus tear.
Study design: We analysed routine England and Wales laboratory surveillance data of acute HBV infection (1995 2000) and data on migration and global HBsAg prevalence.
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine and mediator of acute and chronic inflammatory diseases.
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