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However, in plant cells under normal gravity conditions, the nucleus is positioned by microtubules, since its random migration is prevented by microtubular depolymerization [ 11].
This requires multiple signaling pathways such as phosphatidylinositol-3-kinase (PI3K) and MAPK and TGFβ-stimulated cell migration is prevented by specific inhibition of β1 [ 48].
Additionally cell migration is prevented by the 3 point fixation (TriFix design) which pushes the lens against the posterior capsular bag and keeps it in a secure position.
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Importantly, ecSOD-induced enhancement of VEGF-induced EC migration was prevented by catalase, supporting the role of ecSOD-derived H2O2.
When SOCE activity was inhibited by pharmacological blockade or by siRNA-mediated gene knockdown, the proliferation rate was halted, cell migration was prevented, and metastasis progression was delayed.
Our findings show that TGF-β stimulation of initiating metastatic events, including decreased cell polarization, reduced cell cell contact, and elevated cell invasion and migration, are prevented by CystC treatment.
Functionally, ecSOD, but not ecSOD-ΔHBD, promotes VEGF-induced EC migration in vitro, which is prevented by exogenous application of catalase.
In particular, if the migration of eosinophils or neutrophils is prevented, the ability of professional phagocytes to clear dead cells is severely compromised.
When Hsp-27 phosphorylation is inhibited and functional interaction with actin impaired, migration dependent on F-actin polymerisation is prevented (Chen et al, 2009).
Migration may be prevented with "caging" techniques as described by Durack et al. [37], where an OptEase IVC filter was used as a "cage" for coils.
Cr VI) migration downward could be prevented by vertical barrier in the solely vertical mode.
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