Sentence examples for migration is mediated from inspiring English sources
Owing to the integral role of pS6K in cancer cell migration, it is possible that honokiol-mediated inhibition of migration is mediated through pS6K inhibition.
The way cells explore their surrounding ECM during development and migration is mediated by protrusion of actin-rich structures at the cell front.
These findings support both our hypotheses, first that insect hemocytes can detect and respond to fMLP, and second, that insect hemocyte migration is mediated by eicosanoids.
The way cells explore their surrounding extracellular matrix (ECM) during development and migration is mediated by lamellipodia at their leading edge, acting as an actual motor pulling the cell forward.
In conclusion, we show here that Netrin-1-enhanced SCs migration is mediated by activating p38 MAPK and PI3K-Akt signal cascades via receptor UNC5B, which suggests that Netrin-1 could serve as a new therapeutic strategy and has potential application value for PNS regeneration.
This migration is mediated by the chemokine CXCL12, which is upregulated by seizures.
Together, these results strongly suggested that the enhancement of OECs migration was mediated by reactive astrocyte-derived TNF-α.
We also demonstrate that LTD4 mainly internalizes the CysLT1R, supporting our previous findings that LTD4-induced cell survival, cell proliferation, and cell migration are mediated through the CysLT1R.
To investigate whether the stimulating effect of SMC migration was mediated via the AT1 receptor and whether the counteracting effect of Ang- 1-7) wAng- 1-7ted by the MAS receptor, wasperformediatedmigration assays in the presence or abyence of the AT1 receptor antagonist losartan or the MAS receptor antagonist A-779.
In addition, it has been shown that the effect of Ang II on vascular SMC migration are mediated via an AT1 receptor dependent signaling pathway involving activation of ERK1/2 [9], and that blocking ERK1/2 activation using the MAPK kinase inhibitor PD98059 or antisense oligodeoxynucleotides can significantly attenuate Ang II-stimulated SMC migration [5].
The mediation of mitogenic effects of KGF by ERK1/2 signaling has also been reported in other cell types such as endometrial cells [42], [43] while other effects of KGF such as regulation of cell migration were mediated by MAP Kinase P38 [43].
