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In this study, tumour cells migrate within tracks of ECM molecules, secreted by the leading fibroblasts, whose migration is dependent on Rho-GTPase.
These data suggest that myocardial migration is dependent on epithelial integrity.
This migration is dependent on MUC1 cytoplasmic domain (MUC1-CD) activation of the non-receptor tyrosine kinase, Src, possibly through competitive displacement of an inhibitory Src intramolecular SH3 binding.
Quantitative time-lapse microscopy of primary human fibroblasts exposed to exogenous physiological matrix metalloproteinase (MMP) inhibitors revealed that 3-D migration is dependent on cell seeding density and occurred via highly localized MMP- and tissue inhibitor of metalloproteinases-2-dependent processes.
Hence, the incentive to accumulate human capital in the city is likely to play an important part in the migration decision and, he shows, return migration is dependent on the sector of occupation.
Once the developing neurons reach the core of the olfactory bulb, they detach from the RMS, which is initiated by Reelin and tenascin and move radially toward glomeruli, this migration is dependent on tenascin-R, and differentiate into subtypes of interneurons.
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MMP-2 levels were reduced in the Col8−/− SMCs, and knockdown of MMP-2 in Col8+/+ SMCs partially recapitulated the decreases in migration and 3D gel contraction seen in Col8−/− cells, showing that type VIII collagen-stimulated migration was dependent on MMP-2.
However, the neuropeptide SP activated DCs by eliciting robust Ca2+ elevation, suggesting that DC maturation and migration are dependent on CNI.
These results confirmed that this inhibition of keratinocyte migration was dependent on the epitopes of the blocking antibody, and that laminin-5-β4 interareionecessarycessary for keratinocyte migration.
In our model, fibroblast migration was dependent on HMGB1-TLR2 interaction but did not require RAGE, as previously observed in other cell models [38].
APS-induced monocyte migration was dependent on CXCL12, since neutralizing anti-CXCL12 mAb significantly inhibited (P<0.05) monocyte migration toward APS.
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