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In addition, the pattern of fibroblast migration into fibrin and collagen ECMs was strikingly different.
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CD44 can also mediate wound microvascular endothelial cell migration on fibrogen and invasion into fibrin matrix [ 95].
catalyses the breakdown of fibrin clot, by either converting the inactive circulating plasminogen to active plasmin or directly lysing the fibrin into fibrin degradation products, thereby restoring the normal vascular architecture (Kotb 2013).
Thrombin then acts as a serine protease, which converts fibrinogen into fibrin.
Neither S. mutans cells nor culture supernatants converted fibrinogen into fibrin.
Prothrombin (proenzyme of thrombin) is a vitamin K dependent glycoprotein that converts fibrinogen into fibrin.
Fibronectin and PDGF play a role in fibroblast migration to fibrin clots in collagen hydrogels.
Fibroblast migration to fibrin clots is a critical step in the wound healing process and for this reason fibrin clots are sometimes included within in vitro models.
The coagulation system converts the plasma protein fibrinogen into fibrin, which is a major component of the fluid exudate.
In blood coagulation, thrombin converts fibrinogen into fibrin monomers that polymerize into a clot network.
When tissue damage results in bleeding, fibrinogen is converted at the wound into fibrin by the action of thrombin, a clotting enzyme.
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