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Veland, I. R., Lindbaek, L. & Christensen, S. T. Linking the Primary Cilium to Cell Migration in Tissue Repair and Brain Development.
The chemical nature of biomaterials play important role in cell attachment, proliferation and migration in tissue engineering.
Glutaraldehyde (GLUT) processing, cellular antigens, calcium ions in circulation, and phospholipids present in the native tissue are predominantly responsible for calcification, degeneration, and lack of natural microenvironment for host progenitor cell migration in tissue implants.
To aid in the design of optical probes and the understanding of the resulting spectroscopic signals, modelling of photon scattering and migration in tissue is carried out using Mie theory and Monte Carlo simulations.
Thus efficient gliding might be more relevant for migration in tissue or through cells than for invasion.
Additionally, given the recent discovery that migration in tissue ECMs may more closely resemble 1D migration than 2D migration [34], one could argue that our model should do a superior job of simulating 3D migration than one that incorporated 2D details.
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These hydrogel scaffolds may be useful for studying protein gradient effects on cell behavior and for directing cell migration in tissue-engineering applications.
At this point, the adhesion systems used by lymphocytes for migration in tissues are not known.
Our current understanding of the mechanisms that regulate these and other aspects of collective cell migration in tissues is fairly limited.
Krause, M. & Wolf, K. Cancer cell migration in 3d tissue: Negotiating space by proteolysis and nuclear deformability.
These results strongly imply that ephrinB2 and TBC1d24 regulate neural crest cell migration in a tissue autonomous manner.
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