Recently, the up-regulation of S100 gene family was associated with cellular migration in numerous systems, such as early-stage non-small lung cancer distant metastasis [67], and human keratinocyte trans-activation by the cytokine IL-22 to drive the migration of renewed cells from basal to more differentiated skin layers [68].
Previous studies have revealed that MAPKs are important factors in the regulation of cell migration in numerous cell types in response to cell matrix proteins, growth factors, or cytokines [38].
The involvement of PARP-1 in cell migration was demonstrated in numerous experimental setups.
Furthermore, consistent with the role of potassium channels in two key processes of repair, migration, and proliferation in numerous cell types, the responses to LXA4 on the repair process are mediated by the downstream activation of KATP potassium channels [ 96, 97, 99, 114– 114].
FTS also inhibits tumor growth, cell migration, and energy metabolism in numerous cancer cell lines and many types of cancer cells that exhibit high Ras GTP levels.
This represents an accurate method of determining three-dimensional stem migration and has been used in numerous studies.
Cell migration plays a critical role in numerous physiological processes, including embryonic development, inflammatory responses, wound healing, and angiogenesis, as well as in pathological states such as tumor invasion and metastasis [1], [2].
Adhesion and cell migration are two fundamental steps in numerous diseases, like cancer.
Considering that activation of the Wnt/β-catenin pathway results in the increased migration of numerous cell types in a variety of pathophysiological contexts, inhibition of GSK-3 leading to activation of β-catenin was speculated to stimulate astrocyte migration.
Their ability to induce apoptosis, reduce proliferation, and inhibit tumour cell migration and invasion has been demonstrated in numerous in vitro studies (reviewed in [ 1]).
However, we have recorded regular mass-migrations of prey fish (mainly cyprinids) in numerous lakes in the vicinity of our study site, in other regions of Sweden and also in Denmark.
