It also reflects cell behaviors during a number of developmental events ranging from lateral line migration in zebrafish to border cell migration in Drosophila (Friedl and Gilmour, 2009; Rorth, 2009).
The SRF/Mal pathway has been also investigated in its physiological context in collective migration of border cells in Drosophila oogenesis.
Actin dynamics is required for the migration of individual groups of cells, as in border cell migration in the Drosophila ovary, or large groups of cells, such as those involved in gastrulation in the developing fly embryo [1], [2].
Knockdown of CG6509 using the border cell-specific slbo -GAL4 mildly delayed migration, confirming a requirement in border cells.
Given that TB notification rates are much higher in the countries bordering the EU to the East, this raises the question of what the impact is of cross-border migration in EU countries located at the Eastern border.
They are involved in dorsally directed migration of border cells in invertebrates [56], [57].
There have been other Masses on the U.S.-Mexico border, but this is the first that drew O'Malley and members of the bishops' committee on migration in addition to the border bishops.
Mutations in mbc and elmo result in border cell migration defects in the ovary and myoblast fusion defects in the embryo [25], [26], [27].
In Drosophila, D-Cbl negatively regulates EGFR signaling in dorsoventral patterning during oogenesis [11], in eye development [12], [13], [14], and in border cell migration [15].
In addition, the Rorth lab determined that both Mbc and Spg function redundantly in border cell migration downstream of the receptor PVR [49].
