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Our data indicate that endoderm convergence regulates the medial migration of endocardial precursors, and that premature association of the endocardial and myocardial populations contributes to myocardial migration defects observed in S1pr2/Gα13-deficient S1pr2/Gα13-deficient
It will be critical in future studies to establish if Int6 is capable of controlling both Mek1 and Mek2; our initial MO studies indicate that MEK2 may have a specific role in melanocyte migration (C.A. & E.E.P, unpublished data), raising the possibility that the pigment cell migration defects observed in the int6 morphants also reflect altered MEK signaling.
Neither transgene rescued PQR migration defects observed in sdn-1 (zh20 ).
X11L RNAi-induced phenotypes were close to the background cutoff migration defects observed in the first-round tests (Table S1).
Thus, the migration defects observed after 3 days still persist in the R1-transfected neurons after 6 days.
It was noted that the migration defects observed in the videos seem to be more severe than the segmentation defects observed in the adult flies.
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However, the same kinetin treatment could not rescue the migration defect observed in FD hOE-MSCs with the Boyden's chamber assay (Figure 5).
These data corroborated the migration defect observed in the retinae of ECFAKKO mice.
BANCR was identified as a potential regulator of melanoma cell migration as profound migration defects were observed following BANCR depletion.
Migration defects were observed, comparable with those induced by α5 integrin silencing, with an accumulation of migrating neurons in the ventral region of the cortex (Fig. 4A).
The migration defects we observed in tissue expressing N-APC fragments raised the possibility that N-APC fragments have an effect on cell behaviour that is dominant over the remaining wild-type APC allele.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com