Sentence examples for migration defects have from inspiring English sources

Tangential migration defects have also been reported more recently for olfactory bulb interneurons migrating from the SVZ to the olfactory bulb through the rostral migratory stream, and cortical interneurons which migrate from the medial ganglionic eminences [ 59, 93, 102].

In vivo migration defects have not been reported in FLNb−/− mice but migration is impaired in FLNb−/− fibroblasts, which also have reduced FLNa levels [24].

For example, cell migration defects have been observed in cells lacking normal expression of IKAP/hELP1 [11], [22], [34], [34], and we show here that FD hOE-MSCs exhibit impaired migration compared to control cells.

Subtle neuronal migration defects have been suggested to be causative of RD (66).

However, Gsk3 knock-in S9A/S21A Gsk3 'constitutively active' mice develop normally and migration defects have not been reported (Jiang et al., 2005; Gartner et al., 2006).

Neuronal migration defects have been proposed as a mechanism related to enlarged ventricles and this defect could be common both to schizophrenia and epilepsy.

If the migration defect had been due to background mutations rather than the mir-34 and mir-83 deletions we would not expect the newly isolated double to have the defect.

3. Pign and Pgap1 mutants show defective AVE migration; Cripto mutations have AVE migration defects (D'Andrea et al., 2008).

It was previously shown that for alg-1 dominant-negative alleles ma192 and ma202, respectively 71%and73%3% of worms, have DTC migration defects, strongly suggesting that other miRNAs are involved in the regulation of DTC migrations (Zinovyeva et al. 2014).

At P2, 7 days after electroporation, a time point at which most GFP-positive cells have terminated their migration, shRNA-mediated knockdown by two of the Dpy19l1 shRNAs (sh1769 and sh2069) resulted in cells with neuronal migration defects, whereas the control shRNA had no effect (Fig. 4C-I).

Moreover, upon retesting, some positive lines had stronger migration defects, whereas others were milder; this suggests slight inherent variability of knockdown efficiency.