Sentence examples for migration defect in from inspiring English sources
The electroporated cells (GFP+) migrated to layers 2/3 without obvious migration defect in all experimental conditions.
Both trol germline clones and trol RNAi in the CVM cells resulted in a migration defect in which cells from each of the two migrating collectives merge at the midline (compare Figure 7B with Figure 7, C and D arrows), similar to the phenotype caused by removing FGF signaling (Kadam et al. 2012).
PPARγ-deficient human PMVECs showed a similar migration defect in culture.
Transgenic flies created using these constructs were assayed for their ability to maternally rescue the tre1sctt germ cell migration defect in the context of developing embryos.
No apparent migration defect in Gsk3:Dlx5/6 mice.
Importantly, the migration defect in the developing cortex is specific to excitatory pyramidal neurons.
Supporting this conclusion, PGC migration defects in Mdr49 embryos are substantially ameliorated by a cholesterol-rich diet.
Further dissecting the pathomechanism(s) underlying RHEB-associated ID, we showed severe neuronal migration defects in mouse embryos electroporated with mutant RHEB and an increased incidence of epileptogenic activity postnatally.
El Fatimy R, Miozzo F, Le Mouel A, Abane R, Schwendimann L, Saberan-Djoneidi D et al. Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome.
Conditional knockout of α-catenin in mouse epidermis showed not only adhesion and migration defects in the skin, but marked increases in Ras/MAPK signaling, hyperproliferation, and a significant presence of multinucleated cells (Vasioukhin et al., 2001).
Loss of Abi2 also resulted in cell migration defects in the neocortex and hippocampus, abnormal dendritic spine morphology and density, and severe deficits in short- and long-term memory.
