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The results showed that the expression of miR-139-3p miR-139-3p miR-139-3p lower than that of min-139-5p (Fig. S2A and S2B), and overexpression of miR-139-3p showed no signifiCRCt effecells CRC cell growas and muchation (data not shown).
Furthermore, this was not the result of apoptotic DNA breakage as DNA extracted from the same leaves showed the expected high molecular weight migration (data not shown).
Higher doses of NSC23766 strongly reduced basal Rac1 activity as well as RhoA activity, and inhibited T cell migration (data not shown), most likely because some Rac and RhoA activity is needed for migration [37].
Similarly, PTX partially abolished CM-mediated migration (data not shown).
Neither IL-1β nor PMX464 had any direct effect on neutrophil migration (data not shown).
There was no change in overall participation ratios when controlling for migration (data not shown).
Similar(29)
When a much wider area was included (which usually reflects ancient demographic events), the female migration rate was still larger than the male migration rate (data not shown).
The effect of wiskostatin was dose dependent, although at high doses (50 μM), the epithelial monolayer became disrupted, and at 100 μM, transepithelial migration increased (data not shown), indicating that wiskostatin was not inhibiting the migration of T cells, but was acting on the epithelial cells.
Similar inhibition by anti-E-selectin antibody on tumor cell transendothelial migration was observed in both MDA-MB-435 and MDA-MB-468 cell migration assays (data not shown).
When tested compounds were added either at 20 hpf (when primordium migration begins; data not shown) or 36 hpf (when primordium migrated beyond the yolk extension and 2-3 neuromasts have already been deposited), we observed in all cases a disruption in the migration of the primordium compared to the DMSO control (Fig. 4).
Migration data were not obtained for all deer due to mortalities, collar failure, or because some deer were not collared during capture.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com