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First, we investigated the migration capability in LM1-S4, LM1-S11, LM1, and HCCLM3-R.
VX-680 also decreased migration capability in the majority of cell lines, whereas ZM447439 decreased migration capability of the Saos-2/CDDP6 μg cell line only.
VX-680 decreased migration capability in several OS cell lines, reaching a statistically significant inhibition in IOR/OS9, U-2OS/CDDP4 μg, Saos-2/MTX300, and Saos-2/CDDP6 μg.
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Forced expression also appears to exert an effect on cell matrix adhesion and migration capabilities in this cell line where cells overexpressing EPLINα both migrated at a significantly slower rate and were significantly less able to adhere to the Matrigel basement membrane [ 13].
Relative to controls, cells isolated from As-exposed mice had a significant decrease in migration capability toward ADP in a transwell assay, indicating that As alone can compromise aspects of immune cell function and that this then manifests as a significantly altered innate immune response after viral infection.
Figure 5A C illustrates a significant (P < 0.002) decrease in migration capability that we observed in the KHOS-GFP-shCD49f cell line.
The relationship between Nm23-H1 expression level and cell migration capability was examined in two breast cancer cell lines, the invasive MDA-MB-231 cell line and the non-invasive MCF-7 cell line.
The systemic neutrophil migration capability was investigated in Col2α1-ERα-/ mice and WT littermates by inducing peritoneal inflammation and investigating the number of neutrophils in the peritoneal exudate.
The expression of miR-143 and the migration capability were reduced in PC-3 sphere cells and progressively increased during sphere re-adherent culture.
Mounting evidence on seed dispersal and plant migration rates has revealed that plant migration capability falls short, in various orders of magnitude, of that needed to track ecological optima in the near future [ 2], thus highlighting the importance of within-population standing genetic variation, phenotypic plasticity, and adaptive evolution for plant population survival.
We evaluated whether hUCBSC are capable of inhibiting the migration capability of glioma cells both in vitro and in vivo, and whether this effect is mediated by downregulation of the PI3K-Akt pathway.
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