High expression of Nm23-H1 decellsed cell migration capability, and reduction of Nm23-H1 by RNAi treatment reversed this effect (Figure 7).
However, some cells that escape from retinoic acid action maintain migration capability and invasiveness and express doublecortin.
First, we have analysed morphology, migration capability and cytoskeletal polarisation of the hemocytes at larval and pre-pupal stages.
In this study, the effects of ADAM10-specific siRNAs on the migration capability and invasiveness of HepG2 cells are investigated.
Attenuation of CYP1B1 expression has been found to decrease the proliferative activity, cell migration capability and invasiveness of endometrial and head and neck cancer cell lines [ 9, 10].
Doublecortin is expressed in two cell subtypes considered to be the more aggressive and that show high migration capability and invasiveness.
However, when we digested the sphere cells into single cells for re-adherent culture, the cells gradually showed increased migration capability and reached the level of adherent cells on the fourth day.
As expected, cells co-transfected with the miR-181b mimic and PDCD4 overexpression plasmid showed significantly lower proliferation rates (Fig. 4B) and migration capabilities (Fig. 4C and 4E) and higher apoptosis rates (Fig. 4H and 4I) compared to cells transfected with miR-181b mimic alone.
In scratch migration assay, sub-cytotoxic MJ attenuated the migration capabilities of SGC-7901 and MKN-45 cells in a dose- and time-dependent manner.
The purpose of this study was to investigate the cooperative effects of simvastatin (SIM) and stromal cell-derived factor-1α (SDF-1α) on the osteogenic and migration capabilities of mesenchymal stem cells (MSCs), and construct a cell-free bone tissue engineering system comprising SIM, SDF-1α and scaffold.
