Sentence examples for migration by disrupting from inspiring English sources

We found that a burst increase of intracellular calcium created by an uncaging technique immediately halts the undirected migration by disrupting the ECM-cytoskeleton coupling, as evidenced by the appearance of retrograde F-actin flow.

Therefore, miR-370 expression can increase gastric cancer migration by disrupting the TGFβ signalling (Ref. 76).

In fact, α5 β1 antagonists activate PKA, which then inhibits cell migration by disrupting the formation of stress fibres (Kim et al, 2000b).

In addition, recent studies suggest that attenuation of RACK1 expression suppresses VEGF-mediated cell migration by disrupting the path between VEGF, the PI3K pathway and Rac1 [ 178].

Hydrogen-bonding solvents have been shown to disrupt macrocycle thread interactions in single station rotaxanes, and here addition of 5% [D4]methanol increased the rate of shuttling 100-fold, consistent with lowering the energy barrier to migration by disrupting station macrocycle interactions and thus raising ground-state energies.

The Hsp90 C-terminal inhibitors, including novobiocin and select analogs, inhibited cell migration by disrupting Hsp90α/Aha1 interactions, promoted a loss of cell polarity as indicated by formation of rounded cell morphology and loss of F-actin organization, and caused a defect in cell migration.

BBB permeability has been well documented to be increased by MMPs, which control cell migration across the BBB by disrupting the subendothelial basement membrane and other components of the extracellular matrix and eventually affecting tissue destruction in MS [4], [29].

Correspondingly, we have previously shown that administration of recombinant murine MFG-E8 can decrease neutrophil migration in LPS-induced acute lung injury by disrupting the interaction with integrin αvβ3 [ 24].

Epithelial-mesenchymal transition plays a key role in tumor invasion by disrupting intercellular contacts and enhancing motility and migration of tumor cells to the surrounding tissues [39], [40].

By disrupting the cytoskeleton through Rho-GTPase modulation, both cell migration and tissue integrity can be influenced.

Tβ10 inhibits tumor growth, angiogenesis, migration, and invasion of ovarian cancer in vitro and in vivo studies by disrupting actin polymerization and by inhibiting Ras action [ 24].