Endothelial cell adhesion and migration is fundamental to a number of physiologic processes, including vascular development and angiogenesis.
These studies, as well as our observations, clearly indicate that reelin by its duel function on radial glia and neuronal migration is fundamental to the development of 6-layered lissencephalic as well as gyrencephalic cortices.
In addition some authors have implied that dealing with migration was fundamental to HIV control in Southern Africa [ 23, 44].
Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and excess recruitment of neutrophils and other leukocytes can cause damage to the tissue.
Neuronal migration is fundamental for the development of a fully functional brain, as demonstrated by the implication of defective neuronal migration in a number of neurodevelopmental disorders (Ayala et al., 2007).
In the organism GnRH+ neurons migrate from the olfactory placode to the developing forebrain, to the septum and preoptic area of the hypothalamus and this migration is fundamental for the development of the normal reproductive functions [ 24].
In this study, we investigated whether SPIONs, which are used for magnetic tissue engineering, interfere with cell behavior including adhesion, spreading, or migration, which are fundamental for 3D tissue formation.
In particular, disabled dendritic cell differentiation, maturation, migration, and function are fundamental to this defect, as they are the most potent antigen-presenting cells (APCs) of the immune system, interacting with T and B lymphocyte as well as NK cells to induce and modulate immune responses.
Cell migration and invasion are fundamental components of tumor cell metastases.
Cellular adhesion, migration and invasion are fundamental properties of most cell types during development and normal tissue/cellular function.
