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Consistently, CHARGE iPSC-NCCs showed defective delamination, migration and motility in vitro, and their transplantation in ovo revealed overall defective migratory activity in the chick embryo.
The migration and motility of RH30 cells were examined by a scratch assay and both of the EZH2 depletion lines showed slower scratch recovery than the control (Fig. 5g).
Lower expression of galectin-4 in CRC cells could induce increased cell proliferation, migration and motility.
Therefore, β-catenin could not enter into nucleus to activate the Wnt target genes, which results in the downregulation of cyclin D1, p21, and p15, and the inhibition of cell proliferation, migration, and motility.
Interestingly, we could also see downregulation of TGFβ related molecules including important focal adhesion molecules like Vinculin, Fibronectin, ICAM5, Cadherin 3, Integrin α5 etc. which play major role in cell migration and motility whereas upregulation of tumor suppressor genes and genes involved in cell cycle and DNA metabolism (Tables 1 and 2).
These molecules were involved in manipulating cell migration and motility.
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TGF-α treatment did not change speed, migration distance, and motility pattern of migrating cells.
However, both migration rate and motility, quantified by transwell and time lapse assays respectively, were greater in cells cultured on micro-fibres.
Of particular interest are the genes involved in proteolysis and peptidolysis, cell migration and cell motility, Rho protein signal transduction, regulation of cell adhesion, blood coagulation, and mitosis.
For live imaging of lateral migration and random motility of haemocytes, embryos were mounted ventral side up and imaged live from stage 14 or stage 15, respectively.
Chemokine binding to cognate receptors induces actin dynamics that are a major driving force for T cell migration and chemotactic motility.
More suggestions(15)
migration and differentiation
migration and cleansing
migration and conflict
migration and displacement
migration and climate
migration and relocation
migration and group
migration and youth
migration and urbanisation
migration and asylum
migration and diversity
migration and openness
migration and loss
migration and automation
migration and population
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