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Integrin α6 is dynamically regulated during neuroblast migration and epithelial differentiation in regions of the otocyst that express gata3 [66].
Indeed, membrane depolarization has been shown to regulate cell migration and epithelial wound healing [ 144].
Interferon-γ-inducible protein-10 (IP-10) is an endogenous chemokine that is directly, and indirectly, involved in inflammatory cell migration and epithelial cell survival.
Interferon-γ-inducible protein-10 (IP-10 or CXCL10) plays a role in inflammatory cell migration and epithelial cell survival and migration.
The signals driving inflammatory migration in larvae and pupae remain uncharacterized, but as wounding of the latter triggers integrin-dependent migration and epithelial calcium waves [ 26,55 ], a similar mechanism to that of the embryo may be employed.
aPKC plays an important role in promoting apicobasal polarity of cells, mitotic spindle orientation, directional cell migration and epithelial barrier function; these functions are conserved from model organisms (Caenorhabditis elegans and Drosophila melanogaster) to humans (13 17).
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HMW-MAA was shown to stimulate melanoma cell growth, migration and epithelial-mesenchymal transition promoting tumour progression [19].
PINCH1, an adaptor protein containing five LIM domains, plays an important role in regulating the integrin-mediated cell adhesion, migration and epithelial-mesenchymal transition.
Recently, DUSP6 was shown to inhibit growth, migration and epithelial-to-mesenchymal transition (EMT) of esophagal squamous cell carcinoma and nasopharyngeal carcinoma cells [ 33].
The molecular mechanisms involved in cell migration and epithelial-to-mesenchymal transition were determined by zymography, Western blotting, real-time PCR and immunocytofluorescence.
Importantly, the cell migration and epithelial-mesenchymal transition induced by cancer-associated fibroblasts, or the product of cancer-associated fibroblasts, fibronectin, were reduced by knockdown of β1-integrin in MCF-7R cells.
More suggestions(15)
migration and survival
migration and repair
migration and wear
migration and accumulation
migration and urbanisation
migration and return
migration and development
migration and diversity
migration and filament
migration and replication
migration and death
migration and tissue
migration and mobility
migration and invasion
migration and drift
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