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A role for uPAR in cell migration and assembly of adaptor proteins was also demonstrated by transfecting AdCC cells with an antisense uPAR RNA, which strongly reduced both responses.
This process involves endothelial cell differentiation, migration and assembly in tubular structures.
It has been shown that migration and assembly of various primordia depend on expression of proteins that mediate differential cell adhesion events, and also that differentiated cell lines of ChP vary in expression of these proteins [43] [45].
Previous studies reported that the migration of epithelial cells involves alteration of enterocyte shape and phenotype, including extension of the plasma membrane in the direction of cell migration and assembly of new focal contacts at the leading edge [19], [40], [41].
In angiogenesis, integrins are known to regulate many cell decisions associated with this program by integrating the cellular viability pathways with various processes ranging from ECM deposition and degradation, directional endothelial cell migration and assembly into primitive cords, to lumen formation and vessel maturation [57], [58].
Accordingly, VEGF induces vascular permeability, EC proliferation, migration and assembly into capillary structures.
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Such structures were obtained by simultaneous surface migration and self assembly at the surface of diblock copolymer/homopolymer blends.
A detailed comparative analysis of the cellular and molecular mechanisms that regulate neural progenitor production, cell migration, and circuit assembly can provide much needed insights into the working of neocortical evolution.
These results suggest that FLNa may relay R-Ras signals to integrins to regulate migration and matrix assembly.
Differentiation of beta cells from progenitors is coordinated with morphogenetic events that include delamination of precursors from the ductal epithelium, migration and islet assembly.
For example, stimulating EPHA with EPHRIN-A1 induces endothelial cell migration and vascular assembly through PI3K-mediated activation of the Rac1 GTPase [55].
More suggestions(15)
migration and conflict
migration and survival
migration and cleansing
migration and repair
migration and diversity
migration and filament
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migration and wear
migration and accumulation
migration and urbanisation
migration and return
migration and development
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