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Most abnormalities result from defective migration and alignment of the CC relative to the nucleus.
The impact of FAK knockdown on both migration and alignment varied depending on the topographic cues to which the cells were exposed, with the most significant change observed on the biologically relevant size scale (400 nm).
As extracellular matrix (ECM) and adhesion molecules play critical roles in cell migration and alignment, this study aimed to identify mechanoresponsive genes related to ECM and adhesion in human PDL cells.
The processes of angiogenesis include endothelial cell (EC) proliferation, migration, and alignment into tubular structures.
3D biochemical gradients are of particular note to those interested in studying fundamental biological processes in vitro, including induced cell migration and alignment with RGD 56) and directed neurite extension with nerve growth factor gradients.
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Longitudinal migration and varus−valgus alignment of the femoral stem were analyzed on anteroposterior (AP) radiographs taken immediately after surgery and at FU1 and FU2 by a single examiner using Wristing® software and the associated technique described in a recent study [7].
Surprisingly, at the concentration of Celastrol (2 4 µM) that inhibited cell migration and chromosome alignment, we found a relatively intact MT structure in interphase cells (Figure 3A and B).
By employing a series of experiments which include the time-lapse imaging of cell migration and chromosome alignment as well as biochemical and cell biological approaches, we revealed that inhibition of MT functions was one of the earliest cellular events affected by the novel tubulin-targeting activity of Celastrol.
Contact guided migration of cells and alignment of cell processes were observed on aligned fibers.
This involves a number of highly regulated steps, including activation of myogenic genes, migration, cell cell adhesion and alignment, and finally membrane fusion.
Subsequent time-lapse imaging analyses reveal that inhibition of microtubule-mediated cellular processes, including cell migration and mitotic chromosome alignment, is the earliest events affected by Celastrol.
More suggestions(16)
migration and convergence
migration and activities
migration and cleansing
migration and survival
migration and conflict
migration and displacement
migration and climate
migration and relocation
migration and group
migration and asylum
migration and diversity
migration and openness
migration and loss
migration and romance
migration and differentiation
migration and youth
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