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After migrating to tissues (e.g., lung), monocytes can differentiate into macrophages and dendritic cells which are major phagocytes that engulf M. tb and induce adaptive immunity [ 34, 35].
Although pDCs are probably migrating to tissues and producing IFN- α there, we did not observe any difference in the percentage of circulating pDCs between SLE patients and healthy controls.
Monocytes are an immature type of macrophage, found in peripheral blood and migrating to tissues, maturing if necessary.
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Substantial work needs to be done in understanding what causes different types of carriers to migrate to tissues differentially.
In these cells, the virus might be maintained and could subsequently migrate to tissues and/or organs in infected neonatal monkeys.
It is generally accepted that circulating inflammatory monocytes have a high capacity to migrate to tissues including the vascular wall, where they differentiate into inflammatory macrophages and foam cells in response to oxidized LDL [ 23].
T cells that were found at the DTH skin biopsy highlight the capacity of the induced TAA-specific CD8+ T cells to leave the bloodstream and to migrate to tissues with enhanced expression of the treatment TAA.
BM MSC have previously been identified as progenitors of mesenchymal tissues by migrating to injured tissues to repair them, 19 21 and transplantation of BM MSC for tissue repair has been proposed based on their stem cell qualities.
Macrophages migrating to adipose tissue in response to high-fat feeding overexpress proinflammatory cytokines.
Stimulated monocytes activate pro-survival pathways, migrate to tissues and differentiate into macrophages.
Large phagocytes developed from circulating monocytes that migrate to tissues to eliminate cellular debris and particulate antigens.
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