Sentence examples for migrating PGCs of from inspiring English sources

In mouse development, NANOG becomes detectable in migrating PGCs of E7.75 E8.0 embryos.

The migrating PGCs of wild type embryos were somewhat irregular in shape with large protrusions (Fig. 2A).

Wawersik and Van Doren (2005) have shown that nos is required to initiate and maintain the assembly of spectrosomes in migrating PGCs of stages 11 and 12 embryos, and in nos mutants, spectrosomes are not detected in more than 90% of PGCs.

To define the mechanisms that could contribute to the apparent polarity of migrating PGCs, we first measured the distribution of Cxcr4b on the cell membrane around the cell perimeter.

High levels of H4/H2A R3me2s have also been reported in human GW 19 gonocytes (Eckert et al, 2008), matching the epigenetic profile of migrating PGCs in mice (Seki et al, 2007; Hajkova et al, 2008).

(D ) The number and distribution of filopodia in migrating PGCs overexpressing afap1l1a (dark bars) as compared with control PGCs (light bars).

Specifically, we find that Xist RNA expression, the primary signal for establishment of chromosome silencing, is extinguished in migrating PGCs.

It has been reported that human Oct4 is highly expressed in migrating PGCs, but is silenced once PGCs enter the gonadal ridges and continue to differentiate into more mature gametes [49].

DOI: http://dx.doi.org/10.7554/eLife.05279.029 To assess filopodia function in migrating PGCs, we set out to disrupt their formation by expressing a dominant-negative (DN) form of the Irsp53 protein.

7) The authors describe that 50% of posterior filopodia do not contain actin (in the subsection headed "Migrating PGCs extend specialized filopodia in the direction of migration").

10.7554/eLife.05279.043 Author response image 2. DOI: http://dx.doi.org/10.7554/eLife.05279.043 7) The authors describe that 50% of posterior filopodia do not contain actin (in the subsection headed "Migrating PGCs extend specialized filopodia in the direction of migration").